Anderlecht 1-2 Lyon: result and AI prediction
Anderlecht – Lyon, Europa League, Wednesday, September 16, 2026 at 08:00 PM (GMT). Venue: Lotto Park
Anderlecht is #1 in the table (0 pts) and Lyon #21 (0 pts). 20 places separate the two teams in the table. Anderlecht is unbeaten in its last 5 matches. Anderlecht averages 2.3 goals per match this season. Their last meeting, on July 16, 2022, ended Anderlecht 2-3 Lyon. Absent for Anderlecht: I. Camara, L. Hey, I. Koutsoupias +2.
AI confidence: Medium
AI match recap
Anderlecht bring strong early-season domestic form and a demanding European home environment into their opening league-phase match. Lyon possess the clearer concentration of technical quality in the central attacking lanes, but arrive after a difficult continental qualifying exit and without Duranville. The home side's defensive injuries are the major concern, particularly if Lyon can move Sikan away from the penalty area and sustain attacks around the Anderlecht box. Expect a competitive match in which Anderlecht's early intensity meets Lyon's patient positional play.
Injuries and absences
Anderlecht's missing defensive personnel remove depth at full-back and centre-back, making their protection of the channels a central issue. Lyon are without Duranville, but his absence is less structurally damaging than Anderlecht's defensive shortage; any confirmed Biancone absence would amplify that imbalance.
Form (last 5)
Anderlecht vs Lyon stats
| Anderlecht | Lyon | |
|---|---|---|
| Played | 6 | 0 |
| Goals scored | 14 | 0 |
| Goals conceded | 4 | 0 |
| Clean sheets | 3 | 0 |
Last meetings
- 2022-07-16Anderlecht 2-3 Lyon
- 2022-07-16Anderlecht --- Lyon
Unavailable players
Anderlecht
I. Camara, L. Hey, I. Koutsoupias, K. Sardella, L. Ambros
Lyon
J. Duranville, A. Hamdani, R. Himbert, M. Ouedraogo

Anderlecht
Lyon